Abstract: This research study about development of multimedia focusky–based comic learning media in natural science learning. This type of research is research and development (RnD). The development model in this study refers to Borg and Gall theory which consists of 10 stages. However, in this study, researcher uses 7 stages such as potential and problem, data collection, product design, design validation, design improvement, product testing, and product revision. Data collection methods consist of interviews, observations, and instrument to media experts, material experts, and students. The results of this study include firstly, based on the validation by material and media experts, it can be seen that the validation result by material experts is obtained score of 35 in the very decent category, and validation results from media experts is 38 by a very decent category. Secondly, in the trials conducted on students, it is obtained score of 36 by a very decent category. From the overall validation, it shows very good results so that the multimedia focusky–based comic learning media on natural science learning is decent to be used as a media so teachers are more creative in delivering material, and can support the learning process to be effective, efficient, and fun. ; Penelitian ini mengkaji tentang pengembangan media pembelajaran komik berbasis Multimedia Focusky pada mata pelajaran IPA. Jenis penelitian ini adalah penelitian research and development (R&D). Model pengembangan dalam penelitian ini mengacu pada teori Borg and Gall yang terdiri dari 10 tahap, akan tetatapi dalam penelitian ini peneliti menggunakan 7 tahapan yaitu potensi dan masalah, pengumpulan data, desain produk, validasi desain, perbaikan desain, uji coba produk, revisi produk. Metode pengumpulan data terdiri dari wawancara, observasi, dan instrumen kepada ahli media, ahli materi, dan siswa. Hasil dari penelitian ini yaitu pertama, berdasarkan validasi oleh ahli materi dan media, dapat diketahui hasil validasi oleh ahli materi memperoleh hasil ...